Abstract Search

ea0063gp176 | Benign Thyroid Disorders | ECE2019

Do different initial doses of L-T4 within the range of 10–15 mcg/kg/die influence neurodevelopment during the first two years of life in children with congenital hypothyroidism?

Moracas Cristina , Ciccarelli Gian Paolo , Bravaccio Carmela , Cassio Alessandra , Gastaldi Roberto , Mussa Alessandro , Polizzi Miriam , Vigone Maria Cristina , Wasniewska Malgorzata Gabriela , Weber Giovanna , Salerno Mariacarolina

Background: The initial L-T4 dose in the treatment of congenital hypothyroidism (CH) currently recommended is 1015 mcg/kg/die.Objective: We designed a multicenter randomized trial to evaluate the effects of different starting dose of L-T4 within the range 1015 mcg/kg/die on neurocognitive development in children with CH.Methods: Seventy-two children with CH diagnosed by neonatal screening were enrolled in the study. The...

0 shares

ea0035p853 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Assessment of the hypothalamus–pituitary–adrenal axis with different corticotropin tests in adult patients with Prader–Willi syndrome

Grugni Graziano , Corrias Andrea , Sartorio Alessandro , Beccaria Luciano , Bocchini Sarah , Di Candia Stefania , Fintini Danilo , Iughetti Lorenzo , Mussa Alessandro , Ragusa Letizia , Gargantini Luigi , Salvatoni Alessandro , Delvecchio Maurizio , Chiumello Giuseppe , Crino Antonino

Introduction: Hypothalamicpituitary anomalies are well proven in PraderWilli syndrome (PWS). In this context, it has been previously reported that central adrenal insufficiency (CAI) may be part of the PWS phenotype. However, the diagnostics of CAI is critical and debated, due to the lack of fully reliable tests. Several studies have looked at the clinical usefulness of the low dose (1 μg) short Synacthen test (LDSST) compared to the conventional dose (250 &#9...

0 shares

ePoster Contact

Endocrine Abstracts

Do different initial doses of L-T4 within the range of 10–15 mcg/kg/die influence neurodevelopment during the first two years of life in children with congenital hypothyroidism?

Assessment of the hypothalamus–pituitary–adrenal axis with different corticotropin tests in adult patients with Prader–Willi syndrome

BiosciAbstracts